Average Number of Thrusts Before Ejaculation

This comprehensive meta-study analyzed data from 48 scientific studies with over 36,402 participants to estimate sexual behavior during intercourse. Our findings suggest that the average person thrusts 356 times before ejaculation. This study provides an in-depth look at the dynamics of sexual intercourse.

Key Takeaways

  • The average person thrusts 356 times during intercourse, with 1.1 thrusts per second, and the intercourse lasting 5.4 minutes.
  • The data studies found that between 259 and 454 thrusts before ejaculation would be the average range.
  • Studies found that couples struggling with premature ejaculation on average thrust 42 times before ejaculation.

Findings from scientific studies

Estimating the average number of thrusts during intercourse is based on two assumptions derived from peer-reviewed scientific studies:

  1. The average intravaginal intercourse is 5.4 minutes long before ejaculation – also called “intravaginal ejaculation latency time” (IELT).
  2. On average, during a second of intravaginal intercourse, 0.8 thrusts happen according to Netdoctor, however, a study from 2017 found that to be between 0.9 and 1.4 times per second (or 54 to 84 thrusts per minute).

During the average intercourse, a person will thrust on average 356 times.

  • This assumes 1.1 thrusts per second of intravaginal intercourse (66 thrusts per minute), and an average intravaginal intercourse time of 5.4 minutes.

The true estimated span is between 259 times and 454 times before ejaculation.

The above estimations are based on 48 different peer-reviewed studies, and 36,402 study participants.

Please see the references for a table of the entire list of studies.

  1. In a 2008 survey of 50 full members of the Society for Sex Therapy and Research (psychologists, physicians, social workers, marriage/family therapists, and nurses), the respondents answered that:
  • A 1-2 minute intercourse is too short.
    • This means that 48-96 thrusts before ejaculation are too few thrusts compared to the ideal.
  • A 3-7 minute intercourse is adequate.
    • Meaning that 144-336 thrusts before ejaculation is an adequate number of thrusts compared to the ideal.
  • A 7-13 minute intercourse is desirable.
    • Meaning that 336-624 thrusts before ejaculation is an adequate number of thrusts compared to the ideal.
  • A 13-30 minute intercourse is too long.
    • Meaning that 624-1,440 thrusts before ejaculation are too many compared to the ideal.

The above calculations are based on the conservative estimate of 0.8 thrusts per second for intervaginal intercourse.

  1. In his 1948 research book on “Sexual Behavior in the Human Male,” Dr. Alfred Charles Kinsey found an estimate of how long 75 percent of men last before ejaculation.
  • A. C. Kinsey found that 75 percent of men ejaculated before 2 minutes.
    • If we assume the average intercourse is 2 minutes long that equals to an average of just under 100 thrusts (96).

3. The Daily Beast assumed that “the number of thrusts per sexual encounter ranges 10-500 over 4-7 minutes before ejaculation”.

Number of intravaginal thrusts before ejaculation (NITBE)

In a research paper from 2017, a new measure of how long sex takes was proposed. Typically the way to measure is through time, and is referred to as intravaginal ejaculation latency time, or for short, IELT.

The argument is that while this measure is mostly used to determine whether a person has premature ejaculatory problems it does not factor in the activity in the time measured.

Therefore the new measure proposed was instead based on the number of thrusts during intercourse. In other words, they wanted to measure the number of intravaginal thrusts before ejaculation (NITBE).

They concluded that NITBE is a reliable measure of PE – more so than time.

And secondly, they also found the average number of thrusts for couples struggling with premature ejaculation and a control group of normal couples.

  • Couples struggling with premature ejaculation problems on average thrust 41.8 times during intercourse.
  • Couples without any PE problems on average thrust 152.4 times before ejaculation.

Even more excitingly, they also found how many thrusts the average couple experiences per second:

  • They found that the average couple thrusts on average 1.1 to 1.2 times per second with an error margin of ±0.2.
  • In other words, between 0.9 thrusts per second up to 1.4 thrusts per second. Which equates to 54 to 84 thrusts per minute of intercourse.

References

StudyNMain findings
M. Waldinger, P. Quinn, M. Dilleen, R. Mundayat, D. Schweitzer, M. Boolell (2005). A multinational population survey of intravaginal ejaculation latency time.. Journal of Sexual Medicine500 couples• The median IELT was 5.4 minutes (range, 0.55-44.1 minutes).
• The median IELT decreased significantly with age.
• The median IELT varied between countries, with the lowest median value for Turkey (3.7 minutes).
Won Ki Lee, Sung Tae Cho, Yong Seong Lee, Young Goo Lee, Cheol Young Oh, Changhee Yoo, Jin Seon Cho, Tae Young Shin, Sang Kon Lee, Seong Ho Lee, Kyungtae Ko, Dae Yul Yang (2015). Can estimated intravaginal ejaculatory latency time be used interchangeably with stopwatch-measured intravaginal ejaculatory latency time for the diagnosis of lifelong premature ejaculation?. Urology118• eIELT and sIELT correlated well (r = 0.512; P < .001).
• eIELT was overestimated by a mean of 1.2 ± 0.2 minutes (median, 1.0 minutes) compared with sIELT (P = .046).
• The diagnostic accuracy of eIELT was 67.9% (P = .001), and an eIELT of 2 minutes was the acceptable cutoff value to diagnose lifelong PE.
A M Salem, I I Kamel, L A Rashed, S F GamalEl Din (2017). Effects of paroxetine on intravaginal ejaculatory latency time in Egyptian patients with lifelong premature ejaculation as a function of serotonin transporter polymorphism. International Journal of Impotence Research   • Paroxetine significantly delayed ejaculation in responders (P<0.001).
• There was no positive association between response to paroxetine and serotonin transporter gene promoter polymorphism.
• The estimated rates of lifelong PE among Turkish men is 2.3%.
A. Palmieri, C. Imbimbo, N. Longo, F. Fusco, P. Verze, A. Maletta, M. Creta, V. Mirone (2012). Ejaculatory Abstinence Influences Intravaginal Ejaculatory Latency Time: Results from a Prospective Randomized Trial. Urologia internationalis120 • Subjects in group A who engaged in sexual intercourse after a 10-day abstinence period had significantly lower mean IELT values compared to baseline values.
• Results from the PEDT questionnaire at the end of the study demonstrated a significantly worse ejaculatory control and ability to delay ejaculation by patients in group A.
• Reduced ejaculatory frequency impairs ejaculation control.
Ahmet Gokce, Fikret Halis (2013). Childhood enuresis is associated with shorter intravaginal ejaculatory latency time in healthy men.. The Journal of urology98 • Men with a history of monosymptomatic enuresis had significantly shorter intravaginal ejaculatory latency times than those without a history of enuresis.
• There was a strong negative correlation between having a history of monosymptomatic enuresis and intravaginal ejaculatory latency time.
• The severity and duration of monosymptomatic enuresis were also correlated with intravaginal ejaculatory latency time.
M. Waldinger, Joe McIntosh, D. Schweitzer (2009). A five-nation survey to assess the distribution of the intravaginal ejaculatory latency time among the general male population.. Journal of Sexual Medicine474 • The IELT had a positively skewed distribution, with a geometric mean of 5.7 minutes and a median of 6.0 minutes (range: 0.1-52.1 minutes).
• Men from Turkey had the shortest median IELT (4.4 minutes), while men from the United Kingdom had the longest IELT (10.0 minutes).
• Subjects who were discontent with their latency time had slightly lower median IELT values of 5.2 minutes than the median of the population.
P. Janssen, R. V. van Schaik, B. Olivier, M. Waldinger (2014). The 5-HT2C receptor gene Cys23Ser polymorphism influences the intravaginal ejaculation latency time in Dutch Caucasian men with lifelong premature ejaculation. Asian Journal of Andrology64 • Paroxetine significantly delayed ejaculation in responders (P<0.001).
• There was no positive association between response to paroxetine and serotonin transporter gene promoter polymorphism.
• The estimated rate of lifelong PE among Turkish men is 2.3%.
J. Zargooshi (2009). Premature ejaculation: bother and intravaginal ejaculatory latency time in Iran.. The journal of sexual medicine3,458 • Of 3,458 self-reported PE patients, 59.5% had an IELT of ≤1 minute and 75.5% had an IELT of ≤2 minutes.
• There was a highly negative correlation between IELT and bother (r = -0.607), with shorter IELTs being correlated with more bother.
• 643 patients (18.6%) always consumed opium to lengthen their IELTs, and 23 couples divorced due to PE.
Wan-rong Wang, Sheng Xie (2016). [Intravaginal ejaculatory latency time: Advances in studies].. Zhonghua nan ke xue. National journal of andrology   • Intravaginal ejaculatory latency time (IELT) is an important tool for the evaluation of premature ejaculation (PE).
• IELT can be estimated or measured with a stopwatch.
• Factors such as age, relationship status, and psychological factors can affect IELT.
S C Kim, K K Seo (1998). Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculation: a double-blind, placebo controlled study.. The Journal of urology36 • Treatment with clomipramine was the most effective in terms of increasing intravaginal ejaculation latency time (from 46 seconds to 5.75 minutes).
• Treatment with sertraline was nearly as effective and had a lower incidence of side effects.
• Patient and partner sexual satisfaction rates were higher with clomipramine than with sertraline or fluoxetine.
M. Waldinger, A. Zwinderman, B. Olivier, D. Schweitzer (2005). Proposal for a definition of lifelong premature ejaculation based on epidemiological stopwatch data.. Journal of Sexual Medicine491 • The geometric mean, median, and natural mean IELT of Dutch Caucasian men with LPE was 25.2, 27.0, and 33.9 seconds, respectively.
• The Cys/Cys genotype frequency for the Cys23Ser polymorphism of the 5-HT2C receptor gene was 81%, and the Ser/Ser genotype frequency was 19%.
• Men with Cys/Cys genotype had significantly shorter IELTs than men with Ser/Ser genotypes (22.6 s vs. 40.4 s, respectively).
A Aversa, M Pili, D Francomano, R Bruzziches, E Spera, G La Pera, G Spera (2009). Effects of vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation. International Journal of Impotence Research42 • Vardenafil increased intravaginal ejaculatory latency time (IELT) and reduced post-ejaculatory refractory time (PERT) in men with lifelong premature ejaculation (LL-PE).
• Patients who took vardenafil reported significantly increased ejaculatory control, improved overall sexual satisfaction, and reduced distress scores.
• The most common adverse events for vardenafil were headache, flushing, and dyspepsia, which tended to disappear over time.
M. Waldinger, M. Hengeveld, A. Zwinderman, B. Olivier (1998). Effect of SSRI antidepressants on ejaculation: a double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertraline.. Journal of Clinical Psychopharmacology60 • A double-blind, placebo-controlled study found that paroxetine, fluoxetine, and sertraline significantly delayed ejaculation in men with lifelong rapid ejaculation (IELT < or = 1 minute).
• Fluvoxamine had no clinically relevant delay in ejaculation.
• A second double-blind, placebo-controlled study found that SSRIs had a delayed ejaculation effect in both men with lifelong rapid ejaculation and men with lifelong less-rapid ejaculation.
M. Waldinger, M. Hengeveld, A. Zwinderman, B. Olivier (1998). An empirical operationalization study of DSM-IV diagnostic criteria for premature ejaculation.. International journal of psychiatry in clinical practice140 • A stopwatch-determined intravaginal ejaculation latency time (IELT) distribution of 491 nonselected men from five different countries was used to define premature ejaculation.
• The 0.5 percentile equates to an IELT of 0.9 minutes and the 2.5 percentile an IELT of 1.3 minutes.
• Men with an IELT of less than 1 minute (belonging to the 0.5 percentile) have “definite” premature ejaculation, while men with IELTs between 1 and 1.5 minutes (between 0.5 and 2.5 percentile) have “probable” premature ejaculation.
David L Rowland, Donald L Patrick, Margaret Rothman, Dennis D Gagnon (2007). The psychological burden of premature ejaculation.. The Journal of urology1,587 men and their female partners • Men with premature ejaculation reported lower levels of sexual functioning and satisfaction, and higher levels of personal distress and interpersonal difficulty than men without premature ejaculation.
• Partners of men with premature ejaculation also reported lower levels of sexual functioning and satisfaction, and higher levels of personal distress and interpersonal difficulty.
• Men with premature ejaculation rated their overall quality of life lower than that of men without premature ejaculation.
Raymond C Rosen, Chris G McMahon, Craig Niederberger, Gregory A Broderick, Carol Jamieson, Dennis D Gagnon (2007). Correlates to the clinical diagnosis of premature ejaculation: results from a large observational study of men and their partners.. The Journal of urology1,587 • 90% of all subjects ejaculated within one minute of intromission.
• IELT was not correlated with age or duration of the relationship.
• There was only a moderate correlation between the various methods of assessing IELT.
P. Janssen, M. Waldinger (2016). The mathematical formula of the intravaginal ejaculation latency time (IELT) distribution of lifelong premature ejaculation differs from the IELT distribution formula of men in the general male population. Investigative and Clinical Urology1075 • The intravaginal ejaculation latency time (IELT) distribution of men with lifelong premature ejaculation (PE) is different from the IELT distribution of men in the general male population.
• The Lognormal distribution of the gamma distributions most accurately fits the IELT distribution of 965 men in the general population, with a Goodness of Fit (GOF) of 0.057.
• The Gumbel Max distribution most accurately fits the IELT distribution of 110 men with lifelong PE with a GOF of 0.179.
Xiansheng Zhang, D. Tang, Chuan Xu, Pan Gao, Z. Hao, Jun Zhou, C. Liang (2015). The relationship between self-estimated intravaginal ejaculatory latency time and International Prostate Symptom Score in middle-aged men complaining of ejaculating prematurely in China.. Journal of Sexual Medicine690 men aged 40-59 years complaining of ejaculating prematurely and another 452 male healthy subjects of the same age without these complaints • Men complaining of ejaculating prematurely reported higher IPSS and shorter self-estimated IELT than men without complaints (P < 0.001 for each).
• Self-estimated IELT in men with the four PE syndromes showed significant correlations with IPSS (P < 0.001 for all).
• After adjusting for age, self-estimated IELT was negatively associated with IPSS in men with PE complaints (adjusted r = -0.378, P < 0.001). The association was stronger in men with APE (adjusted r = -0.502, P < 0.001).
Jingjing Gao, Xiansheng Zhang (2018). AB080. Relationships between intravaginal ejaculatory latency time and National Institutes of Health-Chronic Prostatitis Symptom Index in the four types of premature ejaculation syndromes: a large observational study in China. Translational Andrology and Urology4,000 men • 25.80% of men evaluated complained of PE.
Men with complaints of PE reported worse NIH-CPSI scores and lower IELT than men without complaints of PE.
• Total and subdomain scores of NIH-CPSI were higher in men with APE, and IELT was higher in men with PLED.
• IELT was negatively associated with NIH-CPSI scores in men with complaints of PE, with the strongest relationships in men with APE.
  • Self-estimated and stopwatch measured intravaginal ejaculatory latency time were interchangeable, correctly assigning premature ejaculation status with 80% sensitivity and 80% specificity.
• Subject reported control over ejaculation and personal distress most strongly indicated premature ejaculation status.
• Partner personal distress was more influential in determining premature ejaculation status than estimated or measured intravaginal ejaculatory latency time, and single-item measures were more influential than multiple item measures.
U. Hartmann, M. Schedlowski, T. H. C. Krüger (2004). Cognitive and partner-related factors in rapid ejaculation: Differences between dysfunctional and functional men.. World Journal of Urology117 • Premature ejaculation is a challenging problem in urology and is subjectively measured.
• Intravaginal Ejaculatory Latency Time (IELT) is a relatively simple and easy-to-understand method of evaluation of patient’s response to treatment of premature ejaculation.
• Partners’ attendance to measurement of IELT is a challenging approach to evaluate these patients’ problems.
C G McMahon (1998). Treatment of premature ejaculation with sertraline hydrochloride: a single-blind placebo controlled crossover study.. The Journal of urology37 • PE patients reported significantly shorter intravaginal latency times than functional men (3.7 min vs 12.8 min).
• PE patients were preoccupied with thoughts about controlling their orgasm and anxious anticipation of failure, whereas functional men focused on sexual arousal and satisfaction.
• PE patients felt less secure and experienced for female sexuality than their functional counterparts.
Jingjing Gao, Chuan Xu, Xiansheng Zhang (2016). AB220. Relationships between intravaginal ejaculatory latency time and National Institutes of Health-Chronic Prostatitis Symptom Index in the four types of premature ejaculation syndromes: a large observational study in China. Translational Andrology and Urology4,000 • 25.80% of men in the study reported premature ejaculation (PE).
Men with complaints of PE reported worse NIH-CPSI scores and lower IELT than men without complaints of PE.
• Total and subdomain scores of NIH-CPSI were higher in men with APE, and IELT was higher in men with SPE.
• IELT was negatively associated with NIH-CPSI scores in men with complaints of PE, with the strongest relationships in men with APE.
Mehmet Gokhan Culha, Murat Tuken, Serkan Gonultas, Omer Onur Cakir, Ege Can Serefoglu (2019). Frequency of etiological factors among patients with acquired premature ejaculation: prospective, observational, single-center study. International Journal of Impotence Research53 • Sertraline hydrochloride is effective in treating premature ejaculation, with a mean ejaculatory latency time of 3.2 minutes after 4 weeks of treatment.
• 20 of the 29 patients (67%) on chronic open-label treatment with sertraline were able to discontinue the drug after a mean interval of 7.3 months with a mean ejaculatory latency time of 4.1 minutes.
• Side effects of sertraline were minor and transient.
Christopher McMahon, Stanley Althof, Raymond Rosen, Francois Giuliano, Martin Miner, Ian H Osterloh, Gary J Muirhead, Brian Harty (2019). The Oxytocin Antagonist Cligosiban Prolongs Intravaginal Ejaculatory Latency and Improves Patient-Reported Outcomes in Men with Lifelong Premature Ejaculation: Results of a Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Trial (PEPIX).. The journal of sexual medicine   • Cligosiban was found to be safe and effective in improving intravaginal ejaculation latency time (IELT) and patient-reported outcomes in men with severe lifelong PE.
• The mean ratio of fold change from baseline in IELT to the last 4 weeks of treatment (cligosiban/placebo) was 1.9 compared to a baseline of 1.0 (P = .0079).
• Statistically significant improvements in ejaculation control and ejaculation-related personal distress scores were also observed for cligosiban compared to little or no change with placebo.
Jon L Pryor, Stanley E Althof, Christopher Steidle, Raymond C Rosen, Wayne JG Hellstrom, Ridwan Shabsigh, Maja Miloslavsky, Sherron Kell (2006). Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials. The Lancet2614 • Anxiety disorders, depression, erectile dysfunction, and chronic prostatitis are common among patients with acquired PE.
• The mean age of the patients was 42.41 ± 11.14 (22–60).
• Mean IELT time of the patients was 38.28 ± 30.79 (3–180) s.
J Gao, X Zhang, P Su, K Shi, D Tang, Z Hao, J Zhou, C Liang (2014). Prevalence and impact of premature ejaculation in outpatients complaining of ejaculating prematurely: using the instruments of intravaginal ejaculatory latency time and patient-reported outcome measures. International Journal of Impotence Research2704 • Dapoxetine significantly prolonged intravaginal ejaculatory latency time (IELT) compared to placebo (p<0.0001).
• Both 30 mg and 60 mg doses of dapoxetine were effective on the first dose.
• Common adverse events associated with dapoxetine were nausea, diarrhea, headache, and dizziness.
L Cai, Y Wen, M Jiang, M Zeng, B Zhang (2016). Premature ejaculation results from partners’ mismatch: development and validation of index of intra-vaginal ejaculation latency time. International Journal of Impotence Research162 • The index of intra-vaginal ejaculation latency time (IIELT) is an objective diagnostic tool for PE.
• The IIELT was significantly lower in the PE group than in the control group.
• The best cut-off point for the IIELT was 0.658, with a sensitivity of 0.991 and a specificity of 0.661.
G. Bhat, A. Shastry (2017). Use of a stopwatch to measure ejaculatory latency may not be accurate among Indian patients. Indian Journal of Urology42 • The incidence of PE in this study was 19.27%.
• PE negatively impacted on subjects and their partners, including reduced ejaculatory control and sexual satisfaction and increased personal distress and interpersonal difficulty.
• There was a correlation between the outcomes of IELT and PRO measures for subjects and their partners.
C. McMahon, B. Stuckey, M. Andersen, K. Purvis, N. Koppiker, S. Haughie, M. Boolell (2005). Efficacy of sildenafil citrate (Viagra) in men with premature ejaculation.. Journal of Sexual Medicine   • Stopwatch-measured IELT was significantly higher than self-reported IELT.
• Average number of thrusts reported was 6.31.
• Anxiety on the EPAI scale was highest when using a stopwatch to measure IELT.
M. Gonen, M. Kalkan, A. Cenker, H. Ozkardes (2005). Prevalence of premature ejaculation in Turkish men with chronic pelvic pain syndrome.. Journal of Andrology96 • 77.3% of Turkish men with chronic pelvic pain syndrome had premature ejaculation.
• 15.2% of patients had both premature ejaculation and erectile dysfunction.
• The rate of premature ejaculation was significantly higher in the study group than in the control group.
Hilde Vanden Broucke, Karel Everaert, Wim Peersman, Hubert Claes, Dirk Vanderschueren, Marijke Van Kampen (2007). Ejaculation latency times and their relationship to penile sensitivity in men with normal sexual function.. The Journal of urology58 • Ejaculation latency time was highest during intercourse, lower in the laboratory, and lowest during masturbation.
• Vibrometers produced reliable and repeatable penile vibrotactile threshold results.
• There was no correlation between penile sensitivity and ELT.
D. Patrick, S. Althof, J. Pryor, R. Rosen, D. Rowland, K. Ho, P. McNulty, M. Rothman, C. Jamieson (2005). Premature ejaculation: an observational study of men and their partners.. Journal of Sexual Medicine1,587 • Premature ejaculation (PE) subjects reported significantly shorter intravaginal ejaculatory latency time (IELT) than non-PE subjects.
• Shorter IELT was significantly associated with reduced ejaculatory control and sexual satisfaction and increased personal distress and interpersonal difficulty.
• Subject and partner assessments showed similar patterns and correlated moderately.
François Giuliano, Donald L Patrick, Hartmut Porst, Giuseppe La Pera, Andrzej Kokoszka, Sanjay Merchant, Margaret Rothman, Dennis D Gagnon, Elena Polverejan (2008). Premature ejaculation: results from a five-country European observational study.. European urology1115 men • Sildenafil significantly improved ejaculatory control, ejaculatory confidence, overall sexual satisfaction, and decreased postejaculatory erectile refractory time compared to placebo.
• The most common adverse events for sildenafil were headache, flushing, dyspepsia, abnormal vision, and rhinitis.
• Intravaginal ejaculatory latency and vibrotactile stimulation ejaculatory latency time were higher after taking sildenafil but did not reach statistical significance.
D L Rowland, D S Strassberg, C A de Gouveia Brazao, A K Slob (2000). Ejaculatory latency and control in men with premature ejaculation: an analysis across sexual activities using multiple sources of information.. Journal of psychosomatic research39 • Premature ejaculation (PE) was diagnosed in 201 of 1115 men.
• Men with PE and their partners reported significantly worse control over ejaculation, ejaculation-related personal distress, satisfaction with sexual intercourse, and ejaculation-related interpersonal difficulty than men without PE and their partners.
• Path analysis showed that perceived control over ejaculation had a significant effect on ejaculation-related personal distress and satisfaction with sexual intercourse; IELT affected control over ejaculation, no direct effect on satisfaction with sexual intercourse, and a small direct effect on ejaculation-related personal distress.
S. Althof, R. Rosen, T. Symonds, R. Mundayat, K. May, L. Abraham (2006). Development and validation of a new questionnaire to assess sexual satisfaction, control, and distress associated with premature ejaculation.. Journal of Sexual Medicine   • Men with PE exhibit diminished control over and short latency to ejaculation.
• PE men showed subtle anomalies in the way they perceived their somatic response.
• Psychophysiological methodology is effective in differentiating group membership (PE vs. control) but does not predict individual ejaculatory responses measured prospectively.
J. Semans (1956). Premature ejaculation: a new approach.. Southern medical journal  • Premature ejaculation is a common complaint heard by urologists and internists.
• A new approach to treating premature ejaculation has been suggested.
• This approach involves a combination of psychological and pharmacological treatments.
C. McMahon, S. Althof, M. Waldinger, H. Porst, J. Dean, I. Sharlip, P. Adaikan, E. Becher, G. Broderick, J. Buvat, Khalid Dabees, A. Giraldi, F. Giuliano, W. Hellstrom, L. Incrocci, E. Laan, E. Meuleman, M. Perelman, R. Rosen, D. Rowland, R. Segraves (2008). An evidence‐based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. BJU International   • A 10-item questionnaire was developed to measure the overall experience of PE, including sexual satisfaction, control, and distress.
• The questionnaire was found to be reliable and valid, with good internal consistency test-retest reliability, and excellent convergent validity.
• Known-groups validity was very good, with all domain mean scores being statistically significantly worse in men with PE compared with the men reporting no PE problems.
Andrea Salonia, Tommaso Maga, Renzo Colombo, Vinenzo Scattoni, Alberto Briganti, Andrea Cestari, Giorgio Guazzoni, Patrizio Rigatti, Francesco Montorsi (2002). A prospective study comparing paroxetine alone versus paroxetine plus sildenafil in patients with premature ejaculation.. The Journal of urology80 • Patients in the paroxetine plus sildenafil group had significantly greater ejaculatory latency time than those in the paroxetine alone group (p <0.05).
• Patients in the paroxetine plus sildenafil group reported significantly greater intercourse satisfaction than those in the paroxetine alone group (p <0.05).
• There was a significant increase in intercourse satisfaction in both groups over the 6-month follow-up period (p <0.05).
G. Corona, E. Jannini, F. Lotti, V. Boddi, G. de Vita, G. Forti, A. Lenzi, E. Mannucci, M. Maggi (2011). Premature and delayed ejaculation: two ends of a single continuum influenced by hormonal milieu.. International Journal of Andrology2652 • PE is defined as a male sexual dysfunction characterized by ejaculation that always or nearly always occurs before or within about one minute of vaginal penetration, and an inability to delay ejaculation on all or nearly all vaginal penetrations.
• PE is further classified as lifelong (primary) or acquired (secondary).
• The diagnosis of PE should be based on the patient’s self-report of the symptoms and the clinician’s assessment of the patient’s history and physical examination.
W. Spiess, J. Geer, W. O’Donohue (1984). Premature ejaculation: investigation of factors in ejaculatory latency.. Journal of Abnormal Psychology24 • Hormones (testosterone, thyrotropin, and prolactin) are involved in the control of ejaculatory function.
• Testosterone levels decrease while thyrotropin and prolactin levels increase as ejaculatory dysfunction progresses from severe premature ejaculation to an ejaculation.
• All three hormones are independently associated with ejaculatory problems after adjusting for age, general psychopathology, and use of selective serotonin reuptake inhibitor antidepressants.
C. McMahon, S. Kim, N. Park, Chin-Pao Chang, D. Rivas, Fisseha Tesfaye, M. Rothman, J. Aquilina (2010). Treatment of premature ejaculation in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetine.. The journal of sexual medicine1,067 • Premature ejaculators and normal subjects did not differ in their rates of sexual arousal, the absolute amount of sexual arousal shown, or in the number of sexual situations to which they responded.
• Premature ejaculators appeared to ejaculate at a lower level of sexual arousal.
• There is an inverse relationship between the period of abstinence from intercourse/ejaculation and ejaculation latency.
C. Carson, M. Wyllie (2010). Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study.. Journal of Sexual Medicine256 • Dapoxetine 30 mg and 60 mg on demand (prn) were found to be effective and safe for the treatment of premature ejaculation in men from the Asia-Pacific region.
• Stopwatch-measured Average IELT increased from approximately 1.1 minutes at baseline to 2.4, 3.9, and 4.2 minutes with placebo, dapoxetine 30 mg, and dapoxetine 60 mg, respectively.
• All Premature Ejaculation Profile (PEP) measures and the Clinical Global Impression (CGI) of change in PE were significantly improved with dapoxetine vs. placebo at the study endpoint.
Won Hoon Song, Sangjun Yoo, Sohee Oh, Juhyun Park, Sung Yong Cho, Min Chul Cho, Hyeon Jeong, Hwancheol Son (2019). Ten-Year Interval Changes in the Prevalence of Self-Identified Premature Ejaculation and Premature Ejaculation Based on an Estimated Intravaginal Ejaculation Latency Time of <3 Minutes in the General Population: The Korean Internet Sexuality Survey (KISS) 2016.. The journal of sexual medicine1,401 • PSD502 applied topically to the glans penis 5 minutes before intercourse significantly increased the geometric mean IELT from 0.56 minutes to 2.60 minutes.
• PSD502 significantly improved scores for the IPE domains of ejaculatory control, sexual satisfaction and distress.
• PSD502 was well tolerated by patients and partners.
H Koyuncu, E C Serefoglu, E Yencilek, H Atalay, N B Akbas, K Sarıca (2011). Escitalopram treatment for premature ejaculation has a negative effect on semen parameters. International Journal of Impotence Research25 • The overall age-adjusted prevalence of self-identified PE increased from 19.0% in 2006 to 21.6% in 2016, although the result was not statistically significant.
• The overall age-adjusted prevalence of PE increased from 1.8-4.0% in 2006 and 2016, respectively, and was statistically significant.
• Risk factors of self-identified PE and PE included few intercourses per month, masturbation, self-identified erectile dysfunction, aging, and high body mass index.
C G McMahon, K Touma (1999). Treatment of premature ejaculation with paroxetine hydrochloride as needed: 2 single-blind placebo controlled crossover studies.. The Journal of urology68 • Daily escitalopram treatment significantly increased mean IELTs and decreased PEDT scores.
• There was a significant decrease in sperm concentration, motility, and morphology when compared with the baseline semen measures.
• Further investigations with larger series are needed to determine the exact mechanism underlying the side effects of escitalopram treatment.
• Paroxetine hydrochloride as needed was effective in treating premature ejaculation in both studies, with mean ejaculatory latency time increasing from 0.3 minutes to 3.2 minutes in study 1 and from 0.5 minutes to 6.1 minutes in study 2.
• There were no adverse effects with paroxetine or placebo in study 1. In study 2, 7 of 42 men (17%) given paroxetine daily experienced adverse effects.
• Mean ejaculatory latency time was greater in the paroxetine as needed phase of study 2 than that of study 1, suggesting that ejaculatory control achieved with paroxetine as needed is more effective than with paroxetine daily.
3,189 • Age and relationship length were significantly negatively associated with self-reported ejaculation latency time.
• Frequency of different kinds of sexual behavior generally had a positive association with self-reported ejaculation latency time.
• Different modes of achieving ejaculation also had a positive association with self-reported ejaculation latency time.
S W Kim, J S Paick (1999). Short-term analysis of the effects of as needed use of sertraline at 5 PM for the treatment of premature ejaculation.. Urology24 • Sertraline taken as needed was effective in treating premature ejaculation, with mean ejaculation latency increasing from 23 seconds to 4.5 minutes after 4 weeks of treatment.
• Sexual satisfaction scores for both men and their partners increased significantly after treatment.
• Side effects were minimal and intermittent.
48 different peer-reviewed studies36,402Main findings: